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Who gets myasthenia gravis?
Myasthenia gravis occurs in all ethnic groups and both genders. It most
commonly affects young adult women (under 40) and older men (over 60),
but it can occur at any age.
In neonatal myasthenia, the fetus
may acquire immune proteins (antibodies) from a mother affected with
myasthenia gravis. Generally, cases of neonatal myasthenia gravis are
temporary and the child's symptoms
usually disappear within 2-3 months after birth. Other children develop
myasthenia gravis indistinguishable from adults. Myasthenia gravis in
juveniles is uncommon.
Myasthenia gravis is not directly
inherited nor is it contagious. Occasionally, the disease may occur in
more than one member of the same family.
Rarely, children may
show signs of congenital myasthenia or congenital myasthenic syndrome.
These are not autoimmune disorders, but are caused by defective genes
that produce abnormal proteins instead of those which normally would
produce acetylcholine, acetylcholinesterase (the enzyme that breaks down
acetylcholine), or the acetylcholine receptor and other proteins
present along the muscle membrane.
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